Welcome!
The UC Davis Center for Ophthalmic Imaging Research (CHOIR) is a group of neuroscientists, engineers, and clinicians who study the human retina by developing new ways to image it and make inferences about its morphology and physiology. Our team primarily utilizes an interferometric imaging modality called optical coherence tomography (OCT), with which the living human retina can be visualized in three dimensions. We also use adaptive optics (AO), a technique for measuring and correcting blur caused by the eye’s imperfect optics. Together, AO and OCT provide a three-dimensional picture of the retina with enough resolution to see each of its millions of cells. We use these tools to improve our understanding of structure and function in the healthy retina, and to characterize and quantify how they are affected by retinal and other diseases.
News
2022 September 22Kari published optoretinographic measurements using his proto-clinical OCT-ORG system in Optica. Optica wrote a press release describing his work, which was picked up by several popular science magazines. His work also garnered a tweet from @NEIDirector Michael Chiang!
2022 June 13Brennan published results of his experiment using directional OCT to determine whether reduced visibility of outer retinal bands in age-related macular degeneration is due to disorientation of photoreceptors. His paper is in Scientific Reports.
2022 March 18Robert published a review of OCTA, with an emphasis on issues and progress relating to standardization and quantification of angiograms. The work appeared in Light, Science and Applications.
2021 September 22Denise published a novel way to multiplex OCT recordings channels determined by optical path length and carrier frequency orientation. Her paper is in Optics Express.
2021 AugustRavi published a review of efforts to measure retinal neural activity using optical methods over the past fifty years. The review is in the Annals of Translational Medicine.
2020 September 30Denise published kilohertz volumetric imaging with a full-field OCT system with hardware adaptive optics in Biomedical Optics Express.
2020 August 18Mehdi published optoretinographic measurements from single rod photoreceptors in an Editor’s Pick in Optics Letters.
2019 March 5Mehdi published our first measurements of functional responses in cone photoreceptors in Optica. See press releases from Optica and the NIH.